Article

Effects of alcohol on the transcriptome, methylome, and metabolome of <i>in vitro</i> gastrulating human embryonic cells

2024-09-28

Abstract excerpt

<h4>ABSTRACT</h4> Prenatal alcohol exposure (PAE) affects embryonic development, causing a variable fetal alcohol spectrum disorder (FASD) phenotype with neurodevelopmental disorders and birth defects. To explore the effects of PAE on gastrulation, we used an in vitro model with subchronic moderate (20 mM) and severe (70 mM) ethanol exposures during the differentiation of human embryonic stem cells into germ lay...

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Literature Corpus work: 8e608d06-0e7e-5e7b-828f-3c33d8c50f6a
DOI: 10.1101/2024.09.26.615159

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