Article

Design of an exclusive obligate symbiosis for organism-based biological containment

2025-01-05

Abstract excerpt

Biological containment is a critical safeguard for genetically engineered microbes prior to their environmental release to prevent proliferation in unintended regions. However, few biocontainment strategies can support the longer-term microbial survival that may be desired in a target environment without repeated human intervention. Here, we introduce the concept of an orthogonal obligate commensalism for the auto...

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Literature Corpus work: 8d1db7f6-7c74-5958-9f92-e947ece93641
DOI: 10.1101/2025.01.05.631398

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