Article

Computational design of <i>de novo</i> integrated domains enables rational control of pathogen effector recognition in plant NLR immune receptors

2026-07-10

Abstract excerpt

The rapid evolution of plant pathogens poses a persistent threat to global agricultural sustainability, often outpacing the discovery and deployment of natural disease resistance genes. While bioengineering of plant intracellular immune receptors (NLRs) offers a potential solution, developing bespoke immune recognition remains constrained by the laborious characterisation of natural receptors and plant-pathogen in...

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Literature Corpus work: 8cf43adf-7655-5bdc-b73b-40cff32c97d0
DOI: 10.64898/2026.07.10.737686

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