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Article

Two NLR immune receptors acquired high-affinity binding to a fungal effector through convergent evolution of their integrated domain.

eLife - 21 Jul 2021

Białas Aleksandra, Langner Thorsten, Harant Adeline, Contreras Mauricio P, Stevenson Clare Em, Lawson David M, Sklenar Jan, Kellner Ronny, Moscou Matthew J, Terauchi Ryohei, Banfield Mark J, Kamoun Sophien

Abstract excerpt

A subset of plant NLR immune receptors carry unconventional integrated domains in addition to their canonical domain architecture. One example is rice Pik-1 that comprises an integrated heavy metal-associated (HMA) domain. Here, we reconstructed the evolutionary history of Pik-1 and its NLR partner, Pik-2, and tested hypotheses about adaptive evolution of the HMA domain. Phylogenetic analyses revealed that the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34288868
DOI: 10.7554/eLife.66961
PMCID: PMC8294853

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Two NLR immune receptors acquired high-affinity binding to a fungal effector through convergent evolution of their integrated domain.PMID 34288868Read ↗

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