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Prediction of antibody-antigen interaction based on backbone aware with invariant point attention

6 Nov 2024

Abstract excerpt

BACKGROUND: Antibodies play a crucial role in disease treatment, leveraging their ability to selectively interact with the specific antigen. However, screening antibody gene sequences for target antigens via biological experiments is extremely time-consuming and labor-intensive. Several computational methods have been developed to predict antibody-antigen interaction while suffering from the lack of...

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PMID: 39506679
DOI: 10.1186/s12859-024-05961-w

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