Article
Neuronal targeted AAV Micro-Dystrophin restores neurobehavioural co-morbidities, grip strength and motor coordination in <i>mdx52</i> mouse model of Duchenne Muscular Dystrophy
2026-05-26
Abstract excerpt
Duchenne muscular dystrophy (DMD) is a X-linked disorder caused by mutations in the DMD gene, which disrupts production of multiple isoforms of dystrophin in multiple organs namely muscle, heart and brain. While progressive muscle disease and cardiomyopathy are the hallmarks of DMD, over 40% of individuals also experience significant neurobehavioral comorbidities, including autism spectrum disorder (ASD), attenti...
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Identifiers and source
- Literature Corpus work
- 8c91461c-8e61-5ab8-9800-d5d07de128a3
- DOI
- 10.64898/2026.05.22.727055
