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Green Tea-Derived Theabrownin Induces Cellular Senescence and Apoptosis of Hepatocellular Carcinoma via P53 Signaling-Mediated Mechanism Bypassed by JNK Regulation

2021-11-09

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Theabrownin (TB) is a bioactive component of tea and has been reported to exert effects against many human cancers, but its efficacy and mechanism on hepatocellular carcinoma (HCC) with different p53 genotypes remains unclarified. <bold>Methods: </bold>MTT assay, DAPI staining, flow cytometry and SA-β-gal staining were applied to evaluate the effects of TB on HC...

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Literature Corpus work: 8c629a0d-fb59-5e2b-b06f-0a9b5cedb138
DOI: 10.21203/rs.3.rs-1049721/v1

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