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Non-invasive Preimplantation Genetic Testing of Embryonic Genome in Spent Culture Medium

2024-11-13

Abstract excerpt

<h4>ABSTRACT</h4> Traditionally, preimplantation genetic testing (PGT) for in vitro fertilization (IVF) requires invasive trophectoderm (TE) biopsy, which might be detrimental to the embryo. Recently proposed non-invasive PGT (ni-PGT) utilizing cell-free DNA from spent embryo culture medium (SCM) also faces serious challenges in accuracy, especially for monogenic diseases (niPGT-M), due to trace DNA content, mater...

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Literature Corpus work
8c36c4ac-744c-5432-9740-b323b3cfd1cf
DOI
10.1101/2024.11.10.24317049
Open publication

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Non-invasive Preimplantation Genetic Testing of Embryonic Genome in Spent Culture MediumDOI 10.1101/2024.11.10.24317049
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