Article

Arv1 interacts with and regulates the first step of GPI biosynthesis in <i>Candida albicans</i>

2024-11-16

Abstract excerpt

The ubiquitous ARV1 gene shows significant functional conservation across eukaryotes. In humans, it is implicated in early onset epileptic encephalopathy. Evidence suggests that the phenotypes manifested in affected patients are probably due to the deficiency in expression of cell surface GPI anchored proteins. S. cerevisiae Arv1 is proposed to be the elusive GPI flippase that delivers the GPI intermediate from...

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Literature Corpus work: 8bf94de2-20f7-5b8c-87ec-100c4195700d
DOI: 10.1101/2024.11.16.623920

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