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Multi-Omics Screening and Validation of Gut Microbiota and Risk Genes in Idiopathic Inflammatory Myopathies

2026-06-12

Abstract excerpt

<title>Abstract</title> <p> The gut microbiota has emerged as a potential therapeutic target for autoimmune diseases, but its role in inflammatory myopathies remains unclear. Integrating Mendelian randomization, database screening, molecular docking, and in vitro experiments, this study computationally nominates <italic>Lachnoclostridium</italic> as a candidate risk microbe and ENO1 as a candidate risk gene fo...

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Literature Corpus work
8b3f351a-51a3-51a6-8461-471463710b6a
DOI
10.21203/rs.3.rs-9714024/v1
Open publication

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Multi-Omics Screening and Validation of Gut Microbiota and Risk Genes in Idiopathic Inflammatory MyopathiesDOI 10.21203/rs.3.rs-9714024/v1
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