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Article

Gut microbiota and interstitial cystitis: exploring the gut-bladder axis through mendelian randomization, biological annotation and bulk RNA sequencing.

Frontiers in immunology - 1 Jan 2024

Fu Chaowei, Zhao Yu, Zhou Xiang, Lv Jing, Jin Shengkai, Zhou Yuhua, Liu Fengping, Feng Ninghan

Abstract excerpt

Background: Several observational studies have indicated an association between interstitial cystitis and the composition of the gut microbiota; however, the causality and underlying mechanisms remain unclear. Understanding the link between gut microbiota and interstitial cystitis could inform strategies for prevention and treatment. Methods: A two-sample Mendelian randomization analysis was conducted using...

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Bacteria
Gastrointestinal Microbiome
Genome-Wide Association Study
Mendelian Randomization Analysis
Molecular Sequence Annotation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Sequence Analysis, RNA

Urinary Bladder

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Open in PubMed Open full text

Identifiers

PMID: 39399486
DOI: 10.3389/fimmu.2024.1395580
PMCID: PMC11466805

Genes

CHAC2
ERLEC1
PSME4
SPTBN1
STAT3
STAT5A

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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