Article

Classical Monocyte Marker Gene Signatures (CMMGS) Identified by Analysis of Single-Cell and Bulk-RNA Sequencing to Predict Prognosis and Immunotherapy Response in Lung Adenocarcinoma

2023-12-04

Abstract excerpt

<h4>Background: </h4> Classical monocytes, pivotal in the innate immune response, wield considerable influence over cancer prognosis and response to immunotherapy. Our aim was to construct lung adenocarcinoma (LUAD) prognostic signature associated with Classical monocytes. <h4>Methods: </h4> This study encompassed 1,822 samples drawn from diverse public datasets. Initially, we conducted an comprehensive analysis o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8b1f9075-2c49-5def-9776-bec339890fdd
DOI: 10.21203/rs.3.rs-3680738/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Classical Monocyte Marker Gene Signatures (CMMGS) Identified by Analysis of Single-Cell and Bulk-RNA Sequencing to Predict Prognosis and Immunotherapy Response in Lung AdenocarcinomaDOI 10.21203/rs.3.rs-3680738/v1Read

Molecular subtyping based on immune cell marker genes predicts prognosis and therapeutic response in patients with lung adenocarcinoma.Semantic proximity Read

Exploring the prognostic analysis of autophagy and tumor microenvironment based on monocyte cells in lung cancerSemantic proximity Read

Deciphering the immune heterogeneity dominated by RGS1+ TAMs with prognostic implications and identification of novel immunotherapeutic biomarker CD83 in lung adenocarcinomaSemantic proximity Read

Construction of a prognostic model for lung adenocarcinoma tumor endothelial cells and prediction of immunotherapy based on single-cell transcriptome and Bulk transcriptomeSemantic proximity Read

Constructing a Prognostic Model for Non-Small-Cell Lung Cancer Risk Based on Genes Characterising the Differentiation of Myeloid-Derived Suppressor CellsSemantic proximity Read

Integrated analysis of M2 macrophage-related gene prognostic model and single-cell sequence to predict immunotherapy response in lung adenocarcinomaSemantic proximity Read

Identification and Validation of a Novel Signature Based on NK Cell Marker Genes to Predict Prognosis and Immunotherapy Response in Lung Adenocarcinoma by Integrated Analysis of Single-Cell and Bulk RNA-SequencingSemantic proximity Read

Mast cell marker gene signature: prognosis and immunotherapy response prediction in lung adenocarcinoma through integrated scRNA-seq and bulk RNA-seqSemantic proximity Read

Tumor-associated macrophage clusters linked to immunotherapy in a pan-cancer censusSemantic proximity Read

Inflammation in the tumor-adjacent lung as a predictor of clinical outcome in lung adenocarcinomaSemantic proximity Read

Unraveling the role of low‐density lipoprotein‐related genes in lung adenocarcinoma: Insights into tumor microenvironment and clinical prognosisSemantic proximity Read

Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinomaSemantic proximity Read