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Inflammation in the tumor-adjacent lung as a predictor of clinical outcome in lung adenocarcinoma

8 Nov 2023

Abstract excerpt

Approximately 30% of early-stage lung adenocarcinoma patients present with disease progression after successful surgical resection. Despite efforts of mapping the genetic landscape, there has been limited success in discovering predictive biomarkers of disease outcomes. Here we performed a systematic multi-omic assessment of 143 tumors and matched tumor-adjacent, histologically-normal lung tissue with long-term...

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PMID: 37938580
DOI: 10.1038/s41467-023-42327-x

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