Article

Arresting microbiome development limits immune system maturation and resistance to infection

2022-01-18

Abstract excerpt

Disruptions to the intestinal microbiome during weaning lead to long-term negative effects on host immune function. However, the critical host-microbe interactions occurring during weaning required for healthy immune system development remain poorly understood. We find that restricting microbiome maturation during weaning leads to stunted immune system development and increased susceptibility to enteric infection....

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Literature Corpus work: 8afc0a35-ec19-5c04-9196-79986d055ff3
DOI: 10.1101/2022.01.17.476513

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