Article

cpiVAE: Robust and Interpretable Cross-Platform Proteomics Imputation

2025-11-21

Abstract excerpt

Large-scale plasma proteomic studies often use different high-throughput affinity platforms, and measurements of the same protein across platforms are often discordant. Discordance hinders cross-study integration. Improving proteomics data integration would enable more powerful meta-analyses, improve statistical power for biomarker discovery, and provide a better understanding of proteome–phenotype relationships....

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Literature Corpus work: 8ae8e0df-4f3e-5d40-abc6-3ae0950426c3
DOI: 10.1101/2025.11.20.689433

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