Back to search

Article

Unveiling the Anticancer Mechanisms of Prodigiosin by inhibiting of CDK1, TOP2A, and AURKB Expression in Cervical Carcinoma

2024-01-25

Abstract excerpt

Prodigiosin (PG) demonstrates a selective targeting effect on tumor cells. However, its role in cervical carcinoma is still being studied. In this study, we aim to study the specific targets and mechanism of PG in cervical carcinoma. We employed GO enrichment and KEGG analysis to identify core genes in CC patients. To corroborate the expression levels of these core genes, we used staining and RT-PCR on both normal...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8a89c90f-8d21-590a-9e46-ab24bf21fe0c
DOI
10.21203/rs.3.rs-3829039/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Unveiling the Anticancer Mechanisms of Prodigiosin by inhibiting of CDK1, TOP2A, and AURKB Expression in Cervical CarcinomaDOI 10.21203/rs.3.rs-3829039/v1
Screening and Discovery of New Potential Biomarkers and Small Molecule Drugs for Cervical Cancer: A Bioinformatics AnalysisSemantic proximity
Antitumor effects of 9-oxo-10,12-ODAs on human cervical cancer cells: novel insights into CDK regulators and opportunities for cancer therapySemantic proximity
Cordycepin Downregulates Cdk-2 to Interfere with Cell Cycle and Increases Apoptosis by Generating ROS in Cervical Cancer Cells: in vitro and in silico StudySemantic proximity
Targeting<i>CDKN3</i>in cervical cancerSemantic proximity
Targeting Cancer Hallmarks with Epigallocatechin Gallate (EGCG): Mechanistic Basis and Therapeutic TargetsSemantic proximity
Transcriptomic study of the cell death-related pathways of cervical cancer HeLa cells in response to Clinacanthus nutans treatmentSemantic proximity
Interactive bioinformatics analysis for the screening of hub genes and molecular docking of phytochemicals present in kitchen spices to inhibit CDK1 in cervical cancerSemantic proximity
Mitosis Is a Source of Potential Markers for Screening and Survival and Therapeutic Targets in Cervical CancerSemantic proximity
Genomic analysis of cervical carcinoma identifies Alpelisib as a therapeutic option for PIK3CA-mutant cervical carcinoma via the PI3K/AKT pathway.Semantic proximity
Deguelin, an Aurora B Kinase Inhibitor, Exhibits Potent Anti-Tumor Effect in Human Esophageal Squamous Cell CarcinomaSemantic proximity
Natural products targeting the MAPK-signaling pathway in cancer: overviewSemantic proximity
Involvement of FAK-ERK2 signaling pathway in CKAP2-induced proliferation and motility in cervical carcinoma cell linesSemantic proximity
Select a neighboring publication to make it the new centre.