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Cordycepin Downregulates Cdk-2 to Interfere with Cell Cycle and Increases Apoptosis by Generating ROS in Cervical Cancer Cells: in vitro and in silico Study

11 Sept 2018

Abstract excerpt

BACKGROUND: Cordycepin is a small molecule from medicinal mushroom Cordyceps, which has been reported for anticancer properties. OBJECTIVE: In this study, we have focused on the investigation of cordycepin effect on cervical cancer cells with further clarification of possible molecular mechanism. METHOD: We have used cell viability and cell counting assay for cytotoxic effect of cordycepin, flow cytometric assay...

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PMID: 30182857
DOI: 10.2174/1568009618666180905095356

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