Back to search

Article

Dual Biomarker Potential of 18F-PR04.MZ-PET: Assessing Dopaminergic Function and Cerebral Blood Flow in Degenerative Parkinsonian Syndromes

2025-05-30

Abstract excerpt

<title>Abstract</title> <p><italic>Objective</italic> <sup>18</sup>F-PR04.MZ is a new PET radiopharmaceutical for the dopamine transporter (DAT), characterized by enhanced affinity and selectivity for this membrane protein. Previous investigations employing various radiotracers in dementia and movement disorders have suggested that R1 images, derived from compartmental analysis of dynamic studies, can serve as a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8a6866d3-fddc-53f0-b0ac-ed496ca723c1
DOI
10.21203/rs.3.rs-6711157/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Dual Biomarker Potential of 18F-PR04.MZ-PET: Assessing Dopaminergic Function and Cerebral Blood Flow in Degenerative Parkinsonian SyndromesDOI 10.21203/rs.3.rs-6711157/v1
Image-based machine learning model as a tool for classification of [ 18 F]PR04.MZ PET images in patients with parkinsonian syndromeSemantic proximity
Comparison of 18F-DOPA and 18F-DTBZ for PET/CT Imaging of Idiopathic Parkinson’s DiseaseSemantic proximity
Changes of “brain-GI” interplay in Parkinson’s disease: a pilot study of dynamic total-body [11C]CFT PET/CT and kinetic modelingSemantic proximity
Altered glutamate signaling in Parkinson’s disease patients with REM sleep behavior disorderSemantic proximity
Dynamic 11C-PiB PET shows cerebrospinal fluid flow alterations in Alzheimer’s disease and multiple sclerosisSemantic proximity
Reliability of Dopamine Transporter PET Measurements with [18F]FE-PE2I in patients with Parkinson´s DiseaseSemantic proximity
Structural and physiological neurovascular changes in idiopathic Parkinson's disease and its clinical phenotypes.Semantic proximity
An optimized reference tissue method for quantification of tau protein depositions in diverse neurodegenerative disorders by PET with <sup>18</sup>F-PM-PBB3 (<sup>18</sup>F-APN-1607)Semantic proximity
In-vivo Histology of Parkinson’s Disease using Quantitative Multiparametric MappingSemantic proximity
Towards standardization of tau PET imaging corresponding to various tau PET tracer: multi-center phantom studySemantic proximity
Longitudinal Comparative Quantification of [18F]RO948 and florzolotau (18F) PET in the TgF344-AD Rat Model.Semantic proximity
Improved Tau PET SUVR Quantification in 4-Repeat Tau Phenotypes with [18F]PI-2620.Semantic proximity
Select a neighboring publication to make it the new centre.