Article

Integrative Network and Brain Expression Analysis reveals Mechanistic Modules in Ataxia

2018-10-08

Abstract excerpt

<h4>Background</h4> Genetic forms of ataxia are a heterogenous group of degenerative diseases of the cerebellum. Many causative genes have been identified, but a systematic investigation of these genes to understand ataxia pathophysiology has not been performed. <h4>Methods</h4> A manually curated catalogue of 71 genes involved in disorders with progressive ataxias as a major clinical feature was subjected to an...

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Literature Corpus work: 8a670e5a-00a8-56b3-8568-9475462dfb51
DOI: 10.1101/437582

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