Article

Single-cell transcriptomics yield insights into the stress-immune interplay and inform disease risk

2025-06-08

Abstract excerpt

Environmental stress contributes to several disease conditions – including cardiovascular disease, mental illness, and autoimmune disorders – through immune dysregulation. Stress operates through the hypothalamic-pituitary-adrenal and sympathoadrenal axes, leading to peripheral secretion of cortisol and norepinephrine, respectively. While stress profoundly influences immune function, the underlying single-cell and...

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Literature Corpus work: 89b58f26-5ed0-54f0-81ea-7eddc93eced1
DOI: 10.1101/2025.06.05.658150

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