Article

Insights from rare variants into the genetic architecture and biology of youth-onset type 2 diabetes

2023-05-18

Abstract excerpt

<title>Abstract</title> <p>Youth-onset type 2 diabetes (T2D) is a growing public health concern. Its genetic basis and relationship to other forms of diabetes are largely unknown. To gain insight into the genetic architecture and biology of youth-onset T2D, we analyzed exome sequences of 3,005 youth-onset T2D cases and 9,777 ancestry matched adult controls. We identified (a) monogenic diabetes variants in 2.1% of...

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Literature Corpus work: 8959545d-4925-5cff-a041-de2ded1353d7
DOI: 10.21203/rs.3.rs-2886343/v1

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