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Integration single-cell and Bulk RNA-sequencing Data to Reveal Senescence Gene Expression Profiles in Heart Failure

2022-11-14

Abstract excerpt

<h4>Background: </h4> Heart failure(HF) represents one of healthcare's biggest challenges. Although rarely noticed, aging is a crucial risk factor for cardiovascular disease. Our study aims to reveal senescence's role in HF by integrating single cell RNA-sequencing(scRNA-seq) and bulk RNA-sequencing databases. Methods We collected HF heart sample data from the Gene Expression Omnibus database and senescence gene...

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Literature Corpus work
89378ec6-984f-50ac-92d9-c779e76fd29a
DOI
10.21203/rs.3.rs-2250805/v1
Open publication

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Integration single-cell and Bulk RNA-sequencing Data to Reveal Senescence Gene Expression Profiles in Heart FailureDOI 10.21203/rs.3.rs-2250805/v1
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