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Identification and exploration of aging‐related subtypes and distinctive role of SERPINE1 in heart failure based on single‐cell and bulk RNA sequencing data

7 Dec 2023

Abstract excerpt

Aging is a major risk factor for heart failure (HF) and is the leading cause of death worldwide. Currently, the nature of the relationship between aging and HF is not entirely clear. Herein, this study aimed to explore new diagnostic biomarkers, molecular typing and therapeutic strategies for HF by investigating the biological significance of aging-related genes in HF. A total of 157 differentially expressed...

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PMID: 38062883
DOI: 10.1002/jgm.3631

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