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Integrating single-cell and bulk RNA sequencing data establishes a cuproptosis-related gene predictive signature in breast cancer

2025-06-18

Abstract excerpt

<title>Abstract</title> <p>Breast cancer (BRCA) remains the leading cause of cancer-related mortality in women globally. Recent studies implicate dysregulated copper homeostasis in tumorigenesis, with cuproptosis—a copper-dependent cell death mechanism—emerging as a potential therapeutic target. Here, we systematically analyzed the prognostic value of cuproptosis-related genes (CRGs) in BRCA using multi-omics dat...

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Literature Corpus work
892e7592-b5da-52a5-9540-4ada0fda6945
DOI
10.21203/rs.3.rs-6656418/v1
Open publication

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Integrating single-cell and bulk RNA sequencing data establishes a cuproptosis-related gene predictive signature in breast cancerDOI 10.21203/rs.3.rs-6656418/v1
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