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Pan-cancer genetic analysis of cuproptosis and copper metabolism-related gene set

6 Oct 2022

Abstract excerpt

Background: A recent paper has revealed a novel cell death pathway, cuproptosis, a programmed cell death based on copper. This study aimed to evaluate the pan-cancer genomics and clinical association of cuproptosis and copper metabolism-related cell death genes, including SLC25A3, SLC25A37, SLC31A1, FDX1, DLAT, LIAS, ATP7A, ATP7B, COX17, SCO1, SCO2, COX11, and COX19. Methods: By mining multi-omics profiling data,...

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PMID: 36276096
DOI: 10.3389/fonc.2022.952290

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