Article
Cuproptosis-associated genes and immune microenvironment characterization in breast cancer.
Medicine - 16 Dec 2022
Shen Lijuan, He Youwu, Fang Chunhui, Qiu Haiyan, Chen Qing, Huang Fang, Wu Zhengyuan
Abstract excerpt
Excess Cu can cause cell death as a cofactor for essential enzymes. The relationship between cuproptosis-associated genes (CAGs) and breast cancer (BR) is not completely investigated. Here, the transcriptome expression and mutation profile data of BR samples from the Cancer Genome Atlas database were retrieved to identify CAGs. Patients with BR were clustered using consensus clustering. A least absolute shrinkage...
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