Article

From unsupervised clustering to atlas-guided annotation in cohort-scale spatial omics with HiCAT

2026-05-31

Abstract excerpt

Pathologist-annotated tissue regions provide a fundamental reference for examining spatial omics data, yet such annotations are available for a limited number of samples due to the substantial manual effort required. Moreover, these annotations are derived from morphology within individual histology images, which can overlook molecularly defined regions and obscure intra-sample heterogeneity. To address these limi...

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Literature Corpus work: 88f70e44-f422-5e27-8b68-ec4102876513
DOI: 10.64898/2026.05.27.728266

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