Article

A Novel Homozygous Missense Mutation of WEE2 Causes Female Infertility Characterized by Fertilization Failure

2021-07-12

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose</bold>: To investigate the genetic cause of infertility in a female patient due to repeated fertilization failure.<bold>Methods</bold>: Whole exome sequencing was performed to obtain the candidate mutation. Sanger sequencing was used to identify the mutation of the proband and other family members. SIFT, Polyphen-2, and Mutation Taster were used to predict the pathogenicit...

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Literature Corpus work: 883e3807-6ca6-5a29-befb-b3589a7ca9bb
DOI: 10.21203/rs.3.rs-650191/v1

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