Article

Novel autoantibodies in patients with systemic sclerosis and gastrointestinal dysfunction provide insight into disease pathogenesis

2025-08-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Gastrointestinal (GI) dysfunction in systemic sclerosis (SSc) is common and debilitating, yet its underlying mechanisms and related biomarkers are poorly understood. We sought to discover novel autoantibodies in patients with SSc-GI dysfunction and evaluate their clinical relevance. <h4>Methods</h4> Sera from 111 SSc patients enrolled in the Gastrointestinal Assessment Proto...

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Literature Corpus work: 88143151-9c6f-5af9-a2d4-74b46cbb96b1
DOI: 10.1101/2025.08.05.25333061

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