Gut microbiome and metabolomics in systemic sclerosis: feature, link and mechanisms

Abstract excerpt

Systemic sclerosis (SSc) is a rare and highly heterogeneous chronic autoimmune disease characterized by multi-organ and tissue fibrosis, often accompanied by a poor prognosis and high mortality rates. The primary pathogenic mechanisms of SSc are considered to involve tissue fibrosis, autoimmune dysfunction, and microvascular abnormalities. Recent studies have shed light on the gut microbiota (GM) and metabolites...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Inflammatory Myopathies and Dermatomyositis
• Share to Salivary Gland Disorders and Functions
• Share to Systemic Sclerosis and Related Diseases