Article
Severe Type 2 Inflammation Leads to High PAF-Associated Pathology in Chronic Rhinosinusitis with Nasal Polyps (CRSwNP): Hierarchal Cluster Analysis Using Bulk RNA Barcoding and Sequencing
2024-01-17
Abstract excerpt
Platelet-activating factor (PAF) is a phospholipid-derived inflammatory mediator, triggering various inflammatory conditions, including eosinophil activation and recruitment. Despite the unclear mechanism underlying the formation and maintenance of nasal polyp in chronic rhinosinusitis with nasal polyps (CRSwNP), there is strongly indication of its association with type 2 inflammation. This study aimed to quantify...
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Identifiers and source
- Literature Corpus work
- 879e9604-5342-5be0-a256-2cd960a42d09
- DOI
- 10.20944/preprints202401.1320.v1
