Article

Wfs1E864K knock-in mice illuminate the fundamental role of Wfs1 in endocochlear potential production

2023-01-31

Abstract excerpt

<title>Abstract</title> <p>Wolfram syndrome (WS) is a rare neurodegenerative disease encompassing diabetes <italic>mellitus</italic>, diabetes <italic>insipidus</italic>, optic atrophy, hearing loss (HL) and neurological disorders. None of the animal models of the pathology are presenting with an early onset HL, impeding the understanding of the role of Wolframin (WFS1), the protein responsible for WS, in the aud...

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Literature Corpus work: 86ed12a4-d588-500e-a36f-f4894c9d30b5
DOI: 10.21203/rs.3.rs-2467912/v1

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