Article

TMBpred: A bioinformatics tool for precise prediction of the Tumor Mutation Burden in 14 cancer types

2023-03-27

Abstract excerpt

<title>Abstract</title> <p>Immune checkpoint blockade (ICB) is becoming standard-of-care in many types of human malignancies, but patient selection is still imperfect. Tumor mutation burden (TMB) is being evaluated as a biomarker for ICB in clinical trials, but most of the current panels for next generation sequencing (NGS) of tumor samples are focused on drivers and actionable genes and give inaccurate predictio...

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Literature Corpus work: 865f15e2-2f97-514f-916d-5becd1ed69b1
DOI: 10.21203/rs.3.rs-2622080/v1

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