Article

Huntington’s disease age at motor onset is modified by the tandem hexamer repeat in <i>TCERG1</i>

2021-07-19

Abstract excerpt

<h4>Background</h4> Huntington’s disease is caused by an expanded CAG tract in HTT . The length of the CAG tract accounts for over half the variance in age at onset of disease, and is influenced by other genetic factors, mostly implicating the DNA maintenance machinery. We examined a single nucleotide variant, rs79727797, on chromosome 5 in the TCERG1 gene, previously reported to be associated with Huntington’s...

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Literature Corpus work: 865cbefd-6429-5fde-bb10-de4b7abbcd8a
DOI: 10.1101/2021.07.16.452643

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