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Clonorchis sinensis-driven Hepatocarcinogenesis via E2F1-CD24 Transcriptional Axis: Mechanistic and Therapeutic Implications

2025-05-07

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<title>Abstract</title> <p>Hepatocellular carcinoma (HCC) persists as a global health burden with disproportionately high mortality in China's Guangxi region, where endemic <italic>Clonorchis sinensis</italic> (<italic>C. sinensis</italic>) infection coincides with elevated HCC mortality. This study aims to elucidate the oncogenic mechanisms of <italic>C. sinensis</italic> excretory-secretory products (CsESPs) th...

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Literature Corpus work
8645ed22-2999-568c-b32b-86bb85593b0c
DOI
10.21203/rs.3.rs-6378057/v1
Open publication

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