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Genome-wide exploration reveals distinctive northern and southern variants of Clonorchis sinensis in the Far East.

Molecular ecology resources - 1 May 2023

Kinkar Liina, Korhonen Pasi K, Saarma Urmas, Wang Tao, Zhu Xing-Quan, Harliwong Ivon, Yang Bicheng, Fink J Lynn, Wang Daxi, Chang Bill C H, Chelomina Galina N, Koehler Anson V, Young Neil D, Gasser Robin B

Abstract excerpt

Clonorchis sinensis is a carcinogenic liver fluke that causes clonorchiasis-a neglected tropical disease (NTD) affecting ~35 million people worldwide. No vaccine is available, and chemotherapy relies on one anthelmintic, praziquantel. This parasite has a complex life history and is known to infect a range of species of intermediate (freshwater snails and fish) and definitive (piscivorous) hosts. Despite this...

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PMID: 36727564
DOI: 10.1111/1755-0998.13760

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