Article

Evolution of Omicron lineage towards increased fitness in the upper respiratory tract in the absence of severe lung pathology

2024-06-14

Abstract excerpt

The emergence of the Omicron lineage represented a major genetic drift in SARS-CoV-2 evolution. This was associated with phenotypic changes including evasion of pre-existing immunity and decreased disease severity. Continuous evolution within the Omicron lineage raised concerns of potential increased transmissibility and/or disease severity. To address this, we evaluated the fitness and pathogenesis of contemporar...

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Literature Corpus work: 8625dd21-2b0c-54ef-a9f6-c6def55868ca
DOI: 10.1101/2024.06.13.598902

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