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The SARS-CoV-2 Omicron (B.1.1.529) variant exhibits altered pathogenicity, transmissibility, and fitness in the golden Syrian hamster model

2022-01-13

Abstract excerpt

<h4>ABSTRACT</h4> The newly emerging SARS-CoV-2 Omicron (B.1.1.529) variant first identified in South Africa in November 2021 is characterized by an unusual number of amino acid mutations in its spike that renders existing vaccines and therapeutic monoclonal antibodies dramatically less effective. The in vivo pathogenicity, transmissibility, and fitness of this new Variant of Concerns are unknown. We investigate...

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Literature Corpus work
222a44e9-5329-5c02-868b-f051b8c66340
DOI
10.1101/2022.01.12.476031
Open publication

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The SARS-CoV-2 Omicron (B.1.1.529) variant exhibits altered pathogenicity, transmissibility, and fitness in the golden Syrian hamster modelDOI 10.1101/2022.01.12.476031
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