Article

Balanced chromosomal rearrangements offer insights into coding and noncoding genomic features associated with developmental disorders

2022-02-16

Abstract excerpt

<h4>ABSTRACT</h4> Balanced chromosomal rearrangements (BCRs), including inversions, translocations, and insertions, reorganize large sections of the genome and contribute substantial risk for developmental disorders (DDs). However, the rarity and lack of systematic screening for BCRs in the population has precluded unbiased analyses of the genomic features and mechanisms associated with risk for DDs versus normal...

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Literature Corpus work: 8618c225-903a-5fc9-b2f6-ca0378039a8b
DOI: 10.1101/2022.02.15.22270795

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