Article

Rare germline disorders implicate long non-coding RNAs disrupted by chromosomal structural rearrangements

2024-06-19

Abstract excerpt

In recent years, there has been increased focus on exploring the role the non-protein-coding genome plays in Mendelian disorders. One class of particular interest is long non-coding RNAs (lncRNAs), which has recently been implicated in the regulation of diverse molecular processes. However, because lncRNAs do not encode protein, there is uncertainty regarding what constitutes a pathogenic lncRNA variant, and thus...

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Literature Corpus work: 259d073b-58d0-51e0-83f5-84585f92b869
DOI: 10.1101/2024.06.16.24307499

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