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Bulk and Single-Cell Transcriptome Analysis Reveal Shared Key Genes and Patterns of Immune Dysregulation in Sepsis and Systemic Lupus Erythematosus

2023-08-02

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by autoantibody production and multi-organ dysfunction. SLE patients are at an elevated risk of sepsis due to immune dysregulation. Sepsis is a life-threatening condition resulting from dysregulated responses to infection and is the leading cause of ICU admission and death in SLE patients....

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Literature Corpus work
84d0ad73-ded3-5572-91c0-a22b2475ddc5
DOI
10.21203/rs.3.rs-3113873/v1
Open publication

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Bulk and Single-Cell Transcriptome Analysis Reveal Shared Key Genes and Patterns of Immune Dysregulation in Sepsis and Systemic Lupus ErythematosusDOI 10.21203/rs.3.rs-3113873/v1
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