Back to search

Article

Unhealthy lifestyle mediates the adverse effect of childhood traumas on acceleration of aging: analysis of 110,596 UK Biobank participants

2022-04-22

Abstract excerpt

<h4>Background</h4> Accelerated aging makes adults more vulnerable to chronic diseases and death. This study evaluates the association of childhood traumas with a phenotypic aging measure that captures mortality and morbidity risk, and the role of unhealthy lifestyle in mediating these associations. <h4>Methods</h4> We assembled data from 110,596 members of the UK Biobank aged 40-69 years who participated in the b...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
84978748-766c-5d61-84a2-c98c38eadf6d
DOI
10.1101/2022.04.22.22274167
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Unhealthy lifestyle mediates the adverse effect of childhood traumas on acceleration of aging: analysis of 110,596 UK Biobank participantsDOI 10.1101/2022.04.22.22274167
Associations of Early-Life Adversity With Later-Life Epigenetic Aging Profiles in the Multi-Ethnic Study of AtherosclerosisSemantic proximity
Association of Healthy Lifestyle with the Incidence of the Risk of Developing a Broad Range of Diseases: A Prospective Cohort StudySemantic proximity
Associations between exposure to adverse childhood experiences and biological aging: Evidence from the Canadian Longitudinal Study on AgingSemantic proximity
Epigenetic age acceleration and psychosocial stressors in early childhoodSemantic proximity
Early Life Trauma Predicts Affective Phenomenology and the Effects are Partly Mediated by Staging Coupled with Lowered Lipid-Associated Antioxidant DefencesSemantic proximity
Is Early Life Adversity a Trigger towards Inflammageing?Semantic proximity
Characterization and Validation of Adverse Childhood Experiences Data in the All of Us Research ProgramSemantic proximity
The State of Ohio Adversity and Resilience (SOAR) Study Protocol: A Comprehensive, Multimodal, Family-based, Longitudinal Investigation of Risk and Resilience in Mental Health and Substance Use DisordersSemantic proximity
Association of early-life factors with biological age acceleration and the mediating effect of social environment risks in middle-aged and older adults.Semantic proximity
Genetic predisposition, modifiable lifestyles, and their joint effects on human lifespan: evidence from multiple cohort studies.Semantic proximity
Childhood maltreatment, behavioral adjustment, and molecular markers of cellular aging in preschool-aged children: A cohort studySemantic proximity
Additive Effects of Stress and Alcohol Exposure on Accelerated Epigenetic Aging in Alcohol Use DisorderSemantic proximity
Select a neighboring publication to make it the new centre.