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Association of early-life factors with biological age acceleration and the mediating effect of social environment risks in middle-aged and older adults.

Age and ageing - 28 Nov 2024

Liu Xiaojing, Jin Ming, Yang Zeping, Zhang Ziyi, Huang Ninghao, Huang Tao, Li Nan

Abstract excerpt

BACKGROUND: Adverse early-life events influence the health with ageing throughout the life course. However, the effects of combined early-life risks on ageing acceleration in adults and the roles of social environment risks remain unknown. OBJECTIVE: To investigate associations of maternal smoking, breastfeeding and birth weight with accelerated biological age (BA), and to explore genetic-predicted effect and...

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PMID: 39686681
DOI: 10.1093/ageing/afae272

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