Article

Molecular Changes in Prader-Willi Syndrome Neurons Reveals Clues About Increased Autism Susceptibility

2021-08-09

Abstract excerpt

<h4>Background</h4> Prader-Willi syndrome (PWS) is a neurodevelopmental disorder characterized by hormonal dysregulation, obesity, intellectual disability, and behavioral problems. Most PWS cases are caused by paternal interstitial deletions of 15q11.2-q13.1, while a smaller number of cases are caused by chromosome 15 maternal uniparental disomy (PW-UPD). Children with PW-UPD are at higher risk for developing aut...

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Literature Corpus work: 848a7ee5-ad91-5ec7-992e-db288471cfc9
DOI: 10.1101/2021.08.09.455700

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