Article

Comparison of a long-read amplicon sequencing approach to short-read amplicons for microbiome analysis

2025-09-05

Abstract excerpt

Most microbiome studies to date rely on sequencing short amplicons of the 16S rRNA gene on Illumina’s platforms. Because of the short read length, sequences often can be identified reliably only to the family or genus levels. Long read sequencing with whole-length 16S rRNA sequencing can improve taxonomic resolution, but often only to the species level. StrainID is an alternative approach that amplifies a large se...

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Literature Corpus work: 8474c314-ba35-509a-badd-2eeda4dad215
DOI: 10.1101/2025.09.04.674341

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