Finding the right fit: evaluation of short-read and long-read sequencing approaches to maximize the utility of clinical microbiome data

Abstract excerpt

A long-standing challenge in human microbiome research is achieving the taxonomic and functional resolution needed to generate testable hypotheses about the gut microbiota's impact on health and disease. With a growing number of live microbial interventions in clinical development, this challenge is renewed by a need to understand the pharmacokinetics and pharmacodynamics of therapeutic candidates. While...

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