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Mutagenesis and structural studies reveal the basis for the specific binding of SARS-CoV-2 SL3 RNA element with human TIA1 protein

2022-10-24

Abstract excerpt

<title>Abstract</title> <p>Viral RNA-host protein interactions are indispensable during RNA virus transcription and replication. However, the detailed structural and dynamical features of the interactions between viral RNA and various host proteins remain largely elusive. Here, we characterized the binding interface for the SARS-CoV-2 stem-loop 3 (SL3) <italic>cis</italic>-acting element to human TIA1 protein wit...

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Literature Corpus work
84710535-3531-54ba-ad52-1a476ed5f3b7
DOI
10.21203/rs.3.rs-2132183/v1
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Mutagenesis and structural studies reveal the basis for the specific binding of SARS-CoV-2 SL3 RNA element with human TIA1 proteinDOI 10.21203/rs.3.rs-2132183/v1
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