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Structural and Functional Motifs in Influenza Virus RNAs

29 Mar 2018

Abstract excerpt

Influenza A viruses (IAV) are responsible for recurrent influenza epidemics and occasional devastating pandemics in humans and animals. They belong to the Orthomyxoviridae family and their genome consists of eight (-) sense viral RNA (vRNA) segments of different lengths coding for at least 11 viral proteins. A heterotrimeric polymerase complex is bound to the promoter consisting of the 13 5’-terminal and 12...

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PMID: 29651275
DOI: 10.3389/fmicb.2018.00559

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