Article

Desmoglein-2 related Arrhythmogenic Cardiomyopathy: Integrative Genomic and Literature-based analysis with an Italian cohort-Level Validation

2025-08-27

Abstract excerpt

<title>Abstract</title> <p>Desmoglein-2 (DSG2) is a crucial desmosomal cadherin expressed in cardiomyocytes that contributes significantly to the development of arrhythmogenic cardiomyopathy (ACM), a condition characterized by variable onset and clinical presentation. In this study, we conducted an integrative analysis that merges a systematic review of the literature, data from large-scale population databases,...

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Literature Corpus work: 844d8a12-482e-5bc0-b887-eeb2ab845bdb
DOI: 10.21203/rs.3.rs-6957155/v1

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