Article

The analysis of a large dataset of PCR-test results in the community reveals the impact of age, variants and vaccination status on SARS-CoV-2 viral dynamics

2025-12-07

Abstract excerpt

The COVID-19 pandemic has shown the value of large-scale community PCR tests for epidemic surveillance, but the viral load measurements they provide have seldom been exploited to reconstruct within-host trajectories. Because these data are collected for diagnostic rather than research purposes, they are characterized by sparse longitudinal follow-up, heterogeneous sampling, and missing metadata, raising uncertaint...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 84405e6d-842e-5a3d-b85e-880d3054d92c
DOI: 10.64898/2025.12.04.692282

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The analysis of a large dataset of PCR-test results in the community reveals the impact of age, variants and vaccination status on SARS-CoV-2 viral dynamicsDOI 10.64898/2025.12.04.692282Read

SARS-CoV-2 diagnostic testing rates determine the sensitivity of genomic surveillance programsSemantic proximity Read

Low Testing Rates Limit the Ability of Genomic Surveillance Programs to Monitor SARS-CoV-2 Variants: A Mathematical Modelling StudySemantic proximity Read

Epidemiological Parameters of SARS-CoV-2 in the UK during the 2023/2024 Winter: A Cohort StudySemantic proximity Read

Effective real-time transmission estimations incorporating population viral load distributions amid SARS-CoV-2 variants and pre-existing immunitySemantic proximity Read

Quantifying antibody kinetics and RNA detection during early-phase SARS-CoV-2 infection by time since symptom onsetSemantic proximity Read

Viral dynamics of Omicron and Delta SARS-CoV-2 variants with implications for timing of release from isolation: a longitudinal cohort studySemantic proximity Read

Differentiation of SARS-CoV-2 Variants Using RT-qPCRs by Targeting Recurrent Mutation Sites: A Diagnostic Laboratory Experience from Multi-Center Regional Study, August 2020-December 2021, Poland.Semantic proximity Read

Variant‐specific SARS‐CoV‐2 within‐host kineticsSemantic proximity Read

Trajectory of viral load in a prospective population-based cohort with incident SARS-CoV-2 G614 infectionSemantic proximity Read

Geospatial and demographic patterns of SARS-CoV-2 spread in Massachusetts from over 130,000 genomesSemantic proximity Read

SARS-CoV-2 viral load peaks prior to symptom onset: a systematic review and individual-pooled analysis of coronavirus viral load from 66 studiesSemantic proximity Read

Surveillance of COVID-19 in a Vaccinated Population: A Rapid Literature ReviewSemantic proximity Read